Ignite Creation Date:
2024-05-06 @ 6:41 PM
Last Modification Date:
2024-10-26 @ 2:52 PM
Study NCT ID:
NCT05743933
Status:
NOT_YET_RECRUITING
Last Update Posted:
2023-02-24
First Post:
2023-02-16
Brief Title:
Cohort Study of Adrenogenic Autonomic Cortisol Secretion
Sponsor:
Chongqing Medical University
Organization:
Chongqing Medical University
Study Overview
Official Title:
Cohort Study of Adrenogenic Autonomic Cortisol Secretion
Status:
NOT_YET_RECRUITING
Status Verified Date:
2023-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To investige the etiology pathogenesis diagnosis and treatment of adrenogenic autonomic cortisol secretion in Chinese adults
Detailed Description:
With the development of imaging detection technology and its wide application in clinic the detection rate of adrenal incidentaloma AI has been greatly improved In our previous study 189 of AI were accompanied by autonomic cortisol secretion ACS in Chinese The vast majority of ACS is mild MACS Due to the lack of typical Cushing manifestations and the low rate of progression to overt Cushing MACS has received insufficient attention in the past However recent studies have found that MACS have a higher incidence of diabetes hypertension cardiovascular events metabolic bone disease and mortality risk than those with non-functional adenomas With appropriate treatment the complications of MACS patients can be effectively improved However personalized treatment of MACS is a clinical difficulty It is hard to determine whether the cortisol secretion of patients is caused by AI or whether patients will benifit from operation There are some retrospective studies have provided some evidence while prospective studies are lacking The purpose of this study is to prospectively include patients with autonomic cortisol secretion evaluate function and diagnosis develop personalized treatment strategy and follow up the prognosis The research results will provide new evidence for standardized diagnosis and treatment of adrenogenic autonomic cortisol secretion in the future
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None