Ignite Creation Date:
2024-05-06 @ 6:40 PM
Last Modification Date:
2024-10-26 @ 2:52 PM
Study NCT ID:
NCT05741099
Status:
RECRUITING
Last Update Posted:
2023-02-23
First Post:
2023-02-10
Brief Title:
Application and Research of Mesenchymal Stem Cells in Alleviating Severe Development of COVID-19 Infection
Sponsor:
Hebei Medical University
Organization:
Hebei Medical University
Study Overview
Official Title:
The Application and Research of Mesenchymal Stem Cells in Alleviating the Severe Development of Novel Coronavirus Infection to Clarify Its Safety and Effectiveness
Status:
RECRUITING
Status Verified Date:
2023-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study is to evaluate the safety and efficacy of umbilical cord mesenchymal stem cells Therapy for COVID-19
Detailed Description:
Since 2019 novel coronavirus Disease 2019 COVID-19 has spread and prevailed all over the world COVID-19 has a wide range of clinical manifestations of respiratory and non-respiratory symptoms including mild or severe influenza-like syndrome respiratory distress or respiratory failure and may end in multiple organ failure Mesenchymal stem cells MSCS are considered as ideal seed cells for the treatment of various diseases due to their unique immune regulation self-renewal and multiple differentiation potentials The safety of MSC transplantation in the treatment of COVID-19 patients has been proved by a number of clinical studies and has shown good clinical efficacy in shortening the course of the disease alleviating lung damage and reducing the level of inflammatory factors However previous clinical studies mainly focused on the efficacy of MSC transplantation in critically ill patients of COVID-19 ignoring the important role of cell transplantation in delaying or preventing COVID-19 s progress and preventing reinfectionCOVID-19 has spread throughout the country and even the world and the increase in severe and critical cases has caused a great impact on national medical and health resources Stem cell transplantation offers new treatment ideas for COVID-19 patients Since the role of cell transplantation in delaying or preventing the progression of light and medium novel coronavirus infection and preventing reinfection has not been clearly reported this study intends to use MSC transplantation to evaluate the role of stem cells in the occurrence and development of novel coronavirus infection so as to provide an important reference for the prevention and treatment of COVID-19 by MSC
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None