Ignite Creation Date:
2024-05-06 @ 6:40 PM
Last Modification Date:
2024-10-26 @ 2:52 PM
Study NCT ID:
NCT05747547
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2024-02-08
First Post:
2023-02-24
Brief Title:
Retinal Vascular Changes in Patients After Coronavirus Disease 2019 COVID-19
Sponsor:
University Hospital Olomouc
Organization:
University Hospital Olomouc
Study Overview
Official Title:
Retinal Vascular Changes in Patients After Coronavirus Disease 2019 COVID-19 Based on Retinal Oximetry
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The study examines changes in retinal oximetry in patients after COVID-19 disease It aims to analyze and quantify possible retinal microvascular abnormalities that may result from possible post-inflammatory damage to the endothelium of the vessels associated with COVID-19 disease Retinal vascular involvement may indicate similar changes in the vascular system in other organs
Detailed Description:
The retinal blood vessels are the only blood vessels in the body that can be observed directly Patients with COVID-19 pneumonia have been shown to have reduced macular vessel density in the foveal region As a result some layers of the retina atrophy reducing oxygen consumption by the retina Based on this it is expected that patients after COVID-19 pneumonia or after a more severe course of the disease will have normal arterial retinal oxygen saturation but higher venous retinal oxygen saturation and lower arterio-venous difference than patients after mild disease
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None