Ignite Creation Date:
2024-05-05 @ 11:21 AM
Last Modification Date:
2024-10-26 @ 9:04 AM
Study NCT ID:
NCT00005295
Status:
TERMINATED
Last Update Posted:
2024-03-12
First Post:
2000-05-25
Brief Title:
Idiopathic Pulmonary Fibrosis a Case-control Study
Sponsor:
University of New Mexico
Organization:
University of New Mexico
Study Overview
Official Title:
None
Status:
TERMINATED
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not a clinical Trial inadvertently entered in the system
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To determine risk factors for idiopathic pulmonary fibrosis
Detailed Description:
BACKGROUND
Idiopathic pulmonary fibrosis is a progressive and generally fatal disease that causes fibrosis of the pulmonary interstitium While many environmental agents cause diseases clinically similar the etiology of idiopathic pulmonary fibrosis suggests that environmental agents could incite the tissue injury that results in the disease furthermore host characteristics could have an important role in determining the magnitude of the host response to the agent initiating injury
DESIGN NARRATIVE
In this case control study cases were ascertained at the multiple collaborating centers and controls were identified by telephone screening A telephone interview was conducted to collect information needed to test hypotheses concerning cigarette smoking occupational exposure indoor exposures other environmental factors and host factors To limit disease misclassification two pathologists experienced with interstitial diseases of the lung reviewed histopathological material from all cases to exclude entities other than interstitial lung fibrosis and to fully characterize the cases clinically The mortality of this large series of cases was also described
Idiopathic pulmonary fibrosis is a progressive and generally fatal disease that causes fibrosis of the pulmonary interstitium While many environmental agents cause diseases clinically similar the etiology of idiopathic pulmonary fibrosis suggests that environmental agents could incite the tissue injury that results in the disease furthermore host characteristics could have an important role in determining the magnitude of the host response to the agent initiating injury
DESIGN NARRATIVE
In this case control study cases were ascertained at the multiple collaborating centers and controls were identified by telephone screening A telephone interview was conducted to collect information needed to test hypotheses concerning cigarette smoking occupational exposure indoor exposures other environmental factors and host factors To limit disease misclassification two pathologists experienced with interstitial diseases of the lung reviewed histopathological material from all cases to exclude entities other than interstitial lung fibrosis and to fully characterize the cases clinically The mortality of this large series of cases was also described
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01HL043153 | NIH | None | httpsreporternihgovquickSearchR01HL043153 |