Ignite Creation Date:
2024-05-06 @ 6:39 PM
Last Modification Date:
2024-10-26 @ 2:51 PM
Study NCT ID:
NCT05732597
Status:
COMPLETED
Last Update Posted:
2023-02-17
First Post:
2023-02-16
Brief Title:
Acute Coronary Syndrome in Patients With COVID-19
Sponsor:
Bulgarian Cardiac Institute
Organization:
Bulgarian Cardiac Institute
Study Overview
Official Title:
How to Decide Which COVID-19 Patient With Myocardial Infarction to Send to the Cath Lab - A Case Series of COVID-19 Patients With Myocardial Infarction
Status:
COMPLETED
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
ACS-COVID
Brief Summary:
The aim of this study was to find a clinical or laboratory parameter that would help in distinguishing between COVID-19 patients with myocardial infarction MI who have an infarct-related artery IRA and therefore require immediate revascularization and those who have no IRA
Detailed Description:
The coronavirus pandemic has hit the world with its vast contagiousness high morbidity and mortality Apart from the direct damage to the lung tissue the corona virus infection is associated with multiple organ damage including the heart Emerging evidence reveals a direct correlation between COVID-19 and cardiovascular complications such as heart failure myocarditis arrhythmias conduction abnormalities and acute coronary syndromes The SARS-CoV-2 infection can frequently induce coagulation abnormalities that are associated with cardiopulmonary deterioration and death as a possible complication in all patients despite presence or absence of concomitant risk factors and diseases In addition many patients with severe COVID-19 undergo thromboembolic events which seem to be related to this particular coagulopathy One of the most unpleasant and life-threatening types of thromboembolism is the one involving the coronary circulation thus causing a heart attack Many additional problems arise due to this condition eg access to a Cath lab exposure of additional medical personnel more complications and increased mortality for the patients
Invasive angiography for COVID-19 patients is logistically challenging and in some cases there is no intervention target since microcirculatory disease and thrombosis is common in this group Therefore the investigators studied in detail the case series of 10 patients referred for primary percutaneous coronary intervention pPCI for MI in our catheterization laboratory during the course of COVID-19 infection And the investigators set themselves the purpose to evaluate if there are some factors or parameters that could predict the presence of an interventional target - infarct related artery IRA prior to catheterization and to determine their sensitivity and specificity
Invasive angiography for COVID-19 patients is logistically challenging and in some cases there is no intervention target since microcirculatory disease and thrombosis is common in this group Therefore the investigators studied in detail the case series of 10 patients referred for primary percutaneous coronary intervention pPCI for MI in our catheterization laboratory during the course of COVID-19 infection And the investigators set themselves the purpose to evaluate if there are some factors or parameters that could predict the presence of an interventional target - infarct related artery IRA prior to catheterization and to determine their sensitivity and specificity
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None