Ignite Creation Date:
2024-05-06 @ 6:38 PM
Last Modification Date:
2024-10-26 @ 2:52 PM
Study NCT ID:
NCT05738863
Status:
RECRUITING
Last Update Posted:
2023-02-22
First Post:
2023-02-13
Brief Title:
The Effect of Repetative Transcranial Magnetic Stimulation Therapy for Stroke Patients
Sponsor:
Afyonkarahisar Health Sciences University
Organization:
Afyonkarahisar Health Sciences University
Study Overview
Official Title:
The Effect of Repetative Transcranial Magnetic Stimulation Therapy on Lower Urinary System Dysfunctions in Stroke Patients
Status:
RECRUITING
Status Verified Date:
2023-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of our study is to investigate the effect of repetitive transcranial magnetic stimulation therapy rTMS on lower urinary system dysfunctions and detrusor muscle activity in stroke patients
Detailed Description:
Stroke is the second leading cause of death in adults and one of the major causes of long-term disability Functional limitations that develop in the post-stroke period affect the quality of life and activities of daily living of the patients The main purpose of stroke rehabilitation is to improve the quality of life of patients in the areas of physical functional psychological and social health
Post-stroke urinary incontinence PSUI is a common complication that manifests as involuntary loss of urine It has been reported that post-stroke urinary incontinence PSUI affects 40-60 of patients admitted to the hospital after stroke up to 25 still have problems when they are discharged from the hospital and 15 remain incontinence one year later Recent studies have shown that 79 of stroke survivors develop urinary incontinence
It has been reported that this complication is also associated with psychological problems such as low self-esteem and anxiety In addition the presence of urinary incontinence has been considered a marker of stroke severity and a higher mortality rate than those without urinary incontinence Therefore Post-stroke urinary incontinence PSUI management is critical and should be the goal of all stroke health professionals
In recent years there is a need for more effective approaches on neuroplasticity mechanisms in stroke rehabilitation Repetitive transcranial magnetic stimulation rTMS is an innovative approach applied in this field With the application of repetitive transcranial magnetic stimulation rTMS it is aimed to modulate plasticity and restore the normal activity pattern
Repetitive transcranial magnetic stimulation rTMS is a painless non-invasive technique widely used in clinical routine practice to modulate the neural excitability of the human brain High frequency rTMS 5 Hz increases neural activity long term potentiation while low frequency 1 Hz rTMS decreases neural activity long term depression
Previous studies have shown that detrusor overactivity DO constitutes the major urodynamic model of post-stroke urinary incontinence PSUIThis suggests that the brain which is the center of incontinence with detrusor overactivity is a potential target for therapeutic interventions
Repetitive transcranial magnetic stimulation rTMS is a newly developed noninvasive brain stimulation method for the treatment of neurological disordersWhen applied to cortical areas corresponding to the pelvic region it can modulate cortical excitability and induce long-lasting neuroplastic changes
High-frequency rTMS 5 Hz increases neural activity long-term potentiation low-frequency 1 Hz rTMS decreases neural activity long-term depression Clinical studies have shown that inhibition of bladder activity is possible with low frequency 1 Hz rTMS in the primary motor cortex M1
Our primary aim is to investigate the effect of low-frequency rTMS treatment on urinary system dysfunctions in the primary motor cortex M1 in stroke patients
Post-stroke urinary incontinence PSUI is a common complication that manifests as involuntary loss of urine It has been reported that post-stroke urinary incontinence PSUI affects 40-60 of patients admitted to the hospital after stroke up to 25 still have problems when they are discharged from the hospital and 15 remain incontinence one year later Recent studies have shown that 79 of stroke survivors develop urinary incontinence
It has been reported that this complication is also associated with psychological problems such as low self-esteem and anxiety In addition the presence of urinary incontinence has been considered a marker of stroke severity and a higher mortality rate than those without urinary incontinence Therefore Post-stroke urinary incontinence PSUI management is critical and should be the goal of all stroke health professionals
In recent years there is a need for more effective approaches on neuroplasticity mechanisms in stroke rehabilitation Repetitive transcranial magnetic stimulation rTMS is an innovative approach applied in this field With the application of repetitive transcranial magnetic stimulation rTMS it is aimed to modulate plasticity and restore the normal activity pattern
Repetitive transcranial magnetic stimulation rTMS is a painless non-invasive technique widely used in clinical routine practice to modulate the neural excitability of the human brain High frequency rTMS 5 Hz increases neural activity long term potentiation while low frequency 1 Hz rTMS decreases neural activity long term depression
Previous studies have shown that detrusor overactivity DO constitutes the major urodynamic model of post-stroke urinary incontinence PSUIThis suggests that the brain which is the center of incontinence with detrusor overactivity is a potential target for therapeutic interventions
Repetitive transcranial magnetic stimulation rTMS is a newly developed noninvasive brain stimulation method for the treatment of neurological disordersWhen applied to cortical areas corresponding to the pelvic region it can modulate cortical excitability and induce long-lasting neuroplastic changes
High-frequency rTMS 5 Hz increases neural activity long-term potentiation low-frequency 1 Hz rTMS decreases neural activity long-term depression Clinical studies have shown that inhibition of bladder activity is possible with low frequency 1 Hz rTMS in the primary motor cortex M1
Our primary aim is to investigate the effect of low-frequency rTMS treatment on urinary system dysfunctions in the primary motor cortex M1 in stroke patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None