Ignite Creation Date:
2024-05-06 @ 6:37 PM
Last Modification Date:
2024-10-26 @ 2:51 PM
Study NCT ID:
NCT05724654
Status:
COMPLETED
Last Update Posted:
2024-03-01
First Post:
2023-01-11
Brief Title:
Effects of Peanut Consumption on Brain Function
Sponsor:
Maastricht University Medical Center
Organization:
Maastricht University Medical Center
Study Overview
Official Title:
Longer-term Effects of Peanut Consumption on Brain Function in Older Men and Women
Status:
COMPLETED
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Impaired brain vascular function precedes the development of reduced cognitive performance while brain insulin-resistance is also associated with cognitive decline Peanut consumption has already been shown to beneficially affect cognitive performance However underlying mechanisms have not yet been established while well-controlled trials on longer-term effects of peanuts on cognitive performance are highly needed The hypothesis is that longer-term peanut consumption has beneficial effects on regional cerebral blood flow responses primary outcome which may relate to an improved cognitive performance secondary outcome in older men and women Important objectives are to investigate in older adults the effect of 16-week peanut consumption on i brain vascular function in cognitive-control brain areas and ii brain insulin-sensitivity We will also focus on changes in cognitive performance as assessed with a neuropsychological test battery secondary objective Cerebral blood flow responses before brain vascular function and after the administration of intranasal insulin brain insulin-sensitivity will be quantified by the non-invasive gold standard magnetic resonance imaging MRI-perfusion method Arterial Spin Labeling ASL
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None