Viewing Study NCT05729841



Ignite Creation Date: 2024-05-06 @ 6:37 PM
Last Modification Date: 2024-10-26 @ 2:51 PM
Study NCT ID: NCT05729841
Status: COMPLETED
Last Update Posted: 2024-05-21
First Post: 2023-01-16

Brief Title: Study of Ocean Rowing Muscle Metabolism 1 What Effect Does Rowing 3000 Miles Across Atlantic Ocean Have on Calf Muscle Size 2 In the Catabolic State of Extreme Endurance is Muscle Loss Uniform or Can the Human Body Select Depending on Load and Nutrient Availability
Sponsor: University of Exeter
Organization: University of Exeter

Study Overview

Official Title: StORMM 1What Effect Does Rowing 3000 Miles Across Atlantic Ocean Have on Calf Muscle Size StORMM 2 In the Catabolic State of Extreme Endurance is Muscle Loss Uniform or Can the Human Body Select Depending on Load and Nutrient Availability
Status: COMPLETED
Status Verified Date: 2024-05
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: StORMM
Brief Summary: Little is known on the human adaptation to extreme endurance and with the increasing popularity in long duration events we seek to provide insight into the physiological and metabolic adaptation processes of ocean rowing

Rowing 12-18 hours a day will illicit a high energy expenditure and anecdotally people have lost large amounts of body weight and variable amounts of muscle mass particularly in the lower limbs This may provide insights and a potential new model to to study muscle unloading
Detailed Description: Previous research has investigated factors determining muscle loss through bed rest and limb immobilisation These methods are limited in that some do not include inflammation or changes in nutrition which have been shown to be key drivers of muscle loss These studies aim to investigate a potentially new model of muscle unloading

Ocean rowing is an ultra-endurance sport where people spend 35-90 days at sea Usually rowing for a minimum of 12 hours a day in a 2-hour onoff shift pattern with daily food rations Rowers lose body and muscle mass There is likely to be low-grade inflammation nutritional deficit fatigue and rowers do not stand up for the entire crossing Part 1 aims to quantify this muscle loss by inviting rowers in the annual 3000 mile Talisker Whisky Atlantic Challenge 2020 to take part While part 2 aims to continue the work by measuring upper and core muscles as well as lower limb muscles from the first study with the aim of understanding how the body allocates resources in a hypocaloric high energy expenditure environment

Muscle mass of the lower limbs of the rowers will be measured with ultrasound as well as body mass body composition energy expenditure and nutritional intake the week before the race and immediately after arrival in Antigua As well as adding novel insights to the knowledge base around factors affecting ultra endurance performance the results will then be used to inform future intervention studies aimed at preventing muscle loss

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: False
Is a FDA Regulated Device?: False
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None