Ignite Creation Date:
2024-05-06 @ 6:37 PM
Last Modification Date:
2024-10-26 @ 2:51 PM
Study NCT ID:
NCT05728359
Status:
RECRUITING
Last Update Posted:
2023-02-15
First Post:
2022-09-22
Brief Title:
Genomic Determinants of Outcome in Cardiogenic Shock
Sponsor:
Barts The London NHS Trust
Organization:
Barts The London NHS Trust
Study Overview
Official Title:
Prospective Observational Study Investigating Genomic Determinants of Outcome From Cardiogenic Shock GOlDilOCS
Status:
RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
Goldilocs
Brief Summary:
The aim of this project is to understand the heterogeneity of both the immune consequences and treatment responses in CS We will explore this heterogeneity through identification of transcriptomic sub-phenotypes and their association with outcomes including therapeutic responses
Detailed Description:
This is a prospective observational cohort study in 8-10 cardiac centres across Europe We will recruit patients presenting with acute myocardial infarction AMI and CS who are supported medically n100 with extracorporeal membrane oxygenation n50 and with the Impella Device n50 We will also enrol patients who present with either AMI and no evidence of CS n50 or CS due to non-ischaemic pathologies eg myocarditis n50 as comparators The recruitment target is 300 patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None