Ignite Creation Date:
2024-05-06 @ 6:36 PM
Last Modification Date:
2024-10-26 @ 2:51 PM
Study NCT ID:
NCT05723731
Status:
TERMINATED
Last Update Posted:
2024-07-10
First Post:
2023-01-31
Brief Title:
Effect of Transcutaneous Auricular Vagal Nerve Stimulation on Chronic Constipation
Sponsor:
Air Force Military Medical University China
Organization:
Air Force Military Medical University China
Study Overview
Official Title:
Effect of Transcutaneous Auricular Vagal Nerve Stimulation on Chronic Constipation A Randomized Controlled Trial
Status:
TERMINATED
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
A pre-specified interim analysis was conducted as planned we calculated a P-value greater than 057 when comparing response rates between taVNS and sham group resulting in an early termination of the study
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The worldwide prevalence of chronic constipation CC is 15 and women are more likely to develop the disease than men CC have a significant impact on quality of life and increase the burden of national health insurance The conventional medication treatments are primarily symptom-specific and have limited efficacy Previous small sample study had shown the therapeutic potential of transcutaneous auricular vagus nerve stimulation taVNS for irritable bowel syndrome with constipation IBS-C The aim of this study was to investigate whether taVNS could improve defecation condition and constipation symptoms in patients with CC
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None