Ignite Creation Date:
2024-05-06 @ 6:35 PM
Last Modification Date:
2024-10-26 @ 2:50 PM
Study NCT ID:
NCT05711446
Status:
RECRUITING
Last Update Posted:
2023-08-30
First Post:
2022-12-20
Brief Title:
Double Voiding and Post-transplant UTI
Sponsor:
Weill Medical College of Cornell University
Organization:
Weill Medical College of Cornell University
Study Overview
Official Title:
A Randomized Trial of Double Voiding Versus Usual Voiding to Reduce the Incidence of Urinary Tract Infections in Kidney Transplant Recipients
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Urinary tract infections UTI are common in kidney transplant recipients and are an important cause of illness and hospital admissions Past studies have shown that about 1 out of 5 of newly transplanted patients develop UTI within their first 3 months of transplantation Such UTIs increase the risk for blood stream infection and acute rejection of the kidney Improvements in urinary voiding techniques may reduce the frequency of UTI The purpose of this study is to evaluate the benefits of double voiding in kidney transplant recipients
Detailed Description:
Urinary tract infections are common in kidney transplant recipients and are an important cause of morbidity and hospital readmissions Several risk factors for UTI both modifiable and unmodifiable have been described in the literature In normal non-transplant individuals because of the anatomy of the ureter insertion into the bladder that creates a valve-like effect during voiding reflux of urine into the kidney is prevented However after kidney transplantation urine refluxing into the transplanted kidney is common Depending on the surgical technique used for connecting the transplant ureter to the urinary bladder reflux may occur in up to 79 of kidney transplant recipients In addition the routine usage of ureteral stents double J stents for the first 4-6 weeks after transplantation results in reflux Vesicoureteral reflux increases the risk of UTI Double voiding a process of passing urine more than once each time is a technique that may assist the bladder to empty more effectively when urine is left in the bladder By reducing the amount of left-over urine in the bladder after each void double voiding may help reduce the incidence of UTI in kidney transplant recipients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None