Ignite Creation Date:
2024-05-06 @ 6:34 PM
Last Modification Date:
2024-10-26 @ 2:51 PM
Study NCT ID:
NCT05715710
Status:
RECRUITING
Last Update Posted:
2023-02-08
First Post:
2023-01-27
Brief Title:
Correlation Between Deep Medullary Veins and Cognitive Dysfunction in Cerebral Small Vessel Disease
Sponsor:
Zigong No1 Peoples Hospital
Organization:
Zigong No1 Peoples Hospital
Study Overview
Official Title:
Correlation Between Deep Medullary Veins and Cognitive Dysfunction in Cerebral Small Vessel Disease
Status:
RECRUITING
Status Verified Date:
2023-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study aims to obtain the characteristics of cognitive impairment and imaging characteristics of patients with Cerebral small vessel disease CSVD through comprehensive and standardized neuropsychological assessment and multimodal imaging examination The focus is to obtain the characteristics of cognitive impairment and imaging characteristics of patients with CSVD through 30T MRI SWI sequence deep medullary veins DMVs were measured To compare the demographic data hematological indexes imaging scores and the number of DMVs between CSVD groups with and without cognitive impairment and to explore the correlation between deep medullary veins and cognitive dysfunction in cerebral small vessel disease
Detailed Description:
This study aims to obtain the characteristics of cognitive impairment and imaging characteristics of patients with Cerebral small vessel disease CSVD by conducting comprehensive and standardized neuropsychological assessment and multimodal imaging examination deep medullary veins DMVs were measured The demographic data hematological indexes imaging scores and the number of DMVs were compared between the CSVD group with and without cognitive impairment and the risk factors for cognitive impairment in CSVD were analyzed to explore whether DMVs could be an independent risk factor for cognitive impairment in CSVD To establish a multiple model for the risk prediction of cognitive impairment in CSVD and to understand whether the prediction model combined with the number of DMVs has a better prediction effect on cognitive impairment in CSVD In order to find new imaging markers of cognitive impairment in CSVD and provide evidence for early detection and intervention of cognitive impairment in clinical CSVD
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None