Ignite Creation Date:
2024-05-06 @ 6:33 PM
Last Modification Date:
2024-10-26 @ 2:50 PM
Study NCT ID:
NCT05706636
Status:
NOT_YET_RECRUITING
Last Update Posted:
2023-02-02
First Post:
2023-01-21
Brief Title:
T Central Memory Cells in Early Localized Non-Segmental Vitiligo
Sponsor:
Cairo University
Organization:
Cairo University
Study Overview
Official Title:
T Central Memory Cells in Early Localized Non-Segmental Vitiligo and the Effect of Treatment
Status:
NOT_YET_RECRUITING
Status Verified Date:
2023-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Assessing the level of circulating TCMs cluster of differentiation CD 8 CD3C- chemokine receptor CCR7 cluster of differentiation 45 receptor CD45R cells in early localized vitiligo cases prior to treatment and after treatment in comparison to healthy controls This in turn would provide insights regarding the role of TCMs in vitiligo and the role of early treatment in halting disease progression and autoimmune memory formation that accounts for high recurrence rate of vitiligo
Detailed Description:
Assessing the level of circulating TCMs CD8 CD3 CCR7 CD45RO cells in early localized vitiligo cases where samples will be processed and stained for CD8 CD3 CCR7 CCR7 CD45R Multi-parametric flow cytometry will be used to quantify CD3ve CD8ve CCR7ve CD45ROve TCM cells percentage which will be expressed as a percentage from the total lymphocyte gate This will be done prior to treatment and after treatment and will be compared to healthy controls
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None