Ignite Creation Date:
2024-05-06 @ 6:29 PM
Last Modification Date:
2024-10-26 @ 2:49 PM
Study NCT ID:
NCT05680896
Status:
RECRUITING
Last Update Posted:
2023-01-11
First Post:
2022-12-22
Brief Title:
SARS-CoV-2 Infection Among Healthcare Workers
Sponsor:
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Organization:
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Study Overview
Official Title:
The Risk of SARS-CoV-2 Infection and Severity of COVID-19 Among Healthcare Workers With or Without Previous COVID-19 Vaccines
Status:
RECRUITING
Status Verified Date:
2023-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
At present COVID-19 vaccine is considered as the safest economic and effective measure to prevent and control COVID-19 Adaptive immunity including humoral immunity and cellular immunity plays a role in anti-viral responses Cellular immunity includes virus specific B cells and T cells which can provide long-term memory immunity For acute viral infection neutralizing antibody is of great significance in preventing infection while memory cell immunity can maintain a good broad-spectrum and persistence in controlling mutant strains which is a key factor in controlling viral replication after infection and reducing severe disease and death However there is no systematic study on the specific immune response and infection risk of novel coronavirus and there is no definite conclusion on which specific protective immune response induced by vaccine can reduce the risk of infection Therefore this study aims to establish a prospective real-world cohort analyze the correlation between multiple baseline immune protection indicators and infection risk follow up the population with breakthrough infection and monitor the dynamic specific immune response to COVID-19 in peripheral blood and respiratory mucosa This study will provide an important scientific basis for us to scientifically assess the risk of individual infection with COVID-19
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None