Ignite Creation Date:
2024-05-06 @ 6:29 PM
Last Modification Date:
2024-10-26 @ 2:49 PM
Study NCT ID:
NCT05681286
Status:
NOT_YET_RECRUITING
Last Update Posted:
2023-01-31
First Post:
2022-12-25
Brief Title:
CRP to Serum Albumin Ratio in Type 2 DM é Diabetic Nephropathy
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
C-reactive Protein to Serum Albumin Ratio in Type 2diabetic Patients With Diabetic Nephropathy
Status:
NOT_YET_RECRUITING
Status Verified Date:
2022-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
we aimed to compare C-reactive protein to serum albumin CAR level of the T2DM patients with DN to those T2DM without DN
Detailed Description:
Diabetic Nephropathy DN is a serious complication of Diabetes Mellitus associated with chronic and low-grade inflammatory burden affects around 30 of diabetic patients It is the leading cause of end-stage renal failure worldwide and associated with cardio vascular diseases and increases mortality of diabetic patients It characterized by persistent albuminuria raise in arterial blood pressure decrease in glomerular filtration rate GFR It associated with chronic low grade inflammation thats leads to increase glucose and activities inflammation Despite of the pathogenesis of DN is multifactorial but local inflammatory process may result from both the metabolic and hemodynamic affection seen in DN sustained diabetes-related metabolic and haemodynamic perturbations can induce subclinical low-grade renal inflammation and drive kidney from repair response to damage process eventually to renal fibrosis Chronic inflammatory processes not only play a principle role in the progression of micro vascular but also macro vascular complications in type 2 diabetes mellitus An association between low -grade inflammation and type 2 diabetes has been described in recent studies C- reactive protein to serum albumin ratio has attracted great attention recently and used as biomarker in detection disease severity
since type 2 Diabetes Mellitus and Diabetic NephropathyDN is associated with low grade inflammation in recent studies In this study investigator presume that C-reactive protein to serum albumin ratio CAR levels could be associated with the progression of DN in patients with T2DM
since type 2 Diabetes Mellitus and Diabetic NephropathyDN is associated with low grade inflammation in recent studies In this study investigator presume that C-reactive protein to serum albumin ratio CAR levels could be associated with the progression of DN in patients with T2DM
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None