Ignite Creation Date:
2024-05-06 @ 6:27 PM
Last Modification Date:
2024-10-26 @ 2:48 PM
Study NCT ID:
NCT05670093
Status:
RECRUITING
Last Update Posted:
2023-01-04
First Post:
2022-11-19
Brief Title:
Neural Pressure Support Synchrony and Respiratory Muscle Unloading
Sponsor:
Karolinska Institutet
Organization:
Karolinska Institutet
Study Overview
Official Title:
Neural Pressure Support a Randomized Crossover Trial
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
NPS
Brief Summary:
In this study patients who are intubated and on ventilator for more than 24h will be ventilated at three different level of support in Pressure Support and Neural Pressure Support to study patient-ventilator synchrony and muscle unloading
Detailed Description:
This study is an interventional randomized crossover study in intubated and mechanically ventilated patients for more than 24h Eligible patients from whom informed consent is obtained and Pes and Edi catheter are successfully positioned are enrolled in the study Patients will be ventilated in Pressure Support and Neural Pressure Support at three different level of assist baseline 50 and 150 of baseline respectively in randomized order Ventilator curves will be recorded and bloodgas obtained at the end of each study step each lasting 20min
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None