Ignite Creation Date:
2024-05-06 @ 6:26 PM
Last Modification Date:
2024-10-26 @ 2:48 PM
Study NCT ID:
NCT05665556
Status:
RECRUITING
Last Update Posted:
2023-06-29
First Post:
2022-12-19
Brief Title:
REgistry of Pulmonary Arterial Hypertension Associated With CONNECTIVE Tissue Diseases RECONNECTIVE
Sponsor:
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Organization:
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Study Overview
Official Title:
REgistry of Pulmonary Arterial Hypertension Associated With CONNECTIVE Tissue Diseases RECONNECTIVE at the National Institute of Medical Sciences and Nutrition Salvador Zubirán
Status:
RECRUITING
Status Verified Date:
2023-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
RECONNECTIVE
Brief Summary:
The RECONNECTIVE Registry is an observational single center study focused on the subgroup of precapillary pulmonary hypertension related to connective tissue diseases All patients will have hemodynamic confirmation by right heart catheterization and will be follow-up for at least 5 years from admission All patients diagnosed with Group I Pulmonary Arterial Hypertension PAH associated with Connective Tissue Diseases CTD and Group IV Pulmonary Hypertension PH with CTD will be included The purpose of the registry is to learn and understand the clinical outcomes and natural history of the pulmonary arterial hypertension in this subgroup of patients to improve the medical care and treatment
Detailed Description:
Connective tissue diseases represents an important risk factor for pulmonary hypertension either due to vasculopathy or chronic pulmonary thromboembolism These chronic conditions are characterized by being disabling progressive and fatal in a short time and are caused by multiple mechanisms that results in remodeling of the pulmonary microvasculature and right heart failure
In recent years due to international registries we have acquired a better understanding of high-risk subpopulations their poor prognostic factors and the results of specific combination therapies In Mexico the National Institute of Medical Sciences and Nutrition Salvador Zubirán INCMNSZ is a referral center for connective tissue diseases and pathologies of the pulmonary circulation The RECONNECTIVE registry is a five years follow-up cohort that offers the possibility to obtain data regarding to the clinical characteristics and hemodynamic assesment of pulmonary circulation The main objective is to evaluate the clinical course of the PAH in this subgroup of patients and their specific therapy for PAH
In recent years due to international registries we have acquired a better understanding of high-risk subpopulations their poor prognostic factors and the results of specific combination therapies In Mexico the National Institute of Medical Sciences and Nutrition Salvador Zubirán INCMNSZ is a referral center for connective tissue diseases and pathologies of the pulmonary circulation The RECONNECTIVE registry is a five years follow-up cohort that offers the possibility to obtain data regarding to the clinical characteristics and hemodynamic assesment of pulmonary circulation The main objective is to evaluate the clinical course of the PAH in this subgroup of patients and their specific therapy for PAH
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None