Ignite Creation Date:
2024-05-05 @ 6:39 PM
Last Modification Date:
2024-10-26 @ 9:35 AM
Study NCT ID:
NCT00522847
Status:
COMPLETED
Last Update Posted:
2009-02-16
First Post:
2007-08-29
Brief Title:
Biochemical Factors for a Dry Eyed Population
Sponsor:
University of Waterloo
Organization:
University of Waterloo
Study Overview
Official Title:
Biochemical Factors for a Dry Eyed Population
Status:
COMPLETED
Status Verified Date:
2009-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
GARNET
Brief Summary:
The purpose of this study is to compare various symptoms and signs of dry-eye as well as stratify characteristics of the tear film in a group of dry-eyed individuals in comparison to a group of non-dry-eyed people Dry-eye is a condition that significantly impacts the quality of life of the sufferer These are people who are predominantly female and in the older age groups Determining what characterises a person with dry-eyes is of importance to understanding the disease process
Detailed Description:
Dry eye is a multifactorial disease that results in a wide variety of signs and symptoms which are often poorly correlated Recent work has shown that not only are there changes in the composition of the tear film including cytokines and the presence of various mucin species and tear film proteins but also quantifiable changes in both the structure and function of the ocular surface including corneal sensitivity and the appearance of the epithelial cells and the sub-basal neural network To-date no published study has attempted to correlate various clinical and morphological changes found in dry eye with tear film and ocular surface biomarkers
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None