Ignite Creation Date:
2024-05-05 @ 6:39 PM
Last Modification Date:
2024-10-26 @ 9:36 AM
Study NCT ID:
NCT00525551
Status:
COMPLETED
Last Update Posted:
2013-09-11
First Post:
2007-09-04
Brief Title:
Efficacy of Acetylcysteine in Patients Undergoing Surgery for Otosclerosis
Sponsor:
Karolinska University Hospital
Organization:
Karolinska University Hospital
Study Overview
Official Title:
Acetylcystein Vid Stapedotomi
Status:
COMPLETED
Status Verified Date:
2013-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In otosclerosis one of the tiny bones of the middle ear is unable to move normally Sounds cannot be transferred to the inner ear and a conductive hearing loss ensues The disorder is usually treated by an operation where the bone is replaced by a prosthesis This restores hearing at low sound frequencies At high frequencies surgery is less effective The smaller effect at high frequencies is probably caused by surgically induced inner ear damage
Animal studies have shown that the drug acetylcysteine can protect the inner ear against damage It is not known whether the drug has similar effects in humans This study will assess the efficacy of acetylcysteine in patients undergoing surgery for otosclerosis
Animal studies have shown that the drug acetylcysteine can protect the inner ear against damage It is not known whether the drug has similar effects in humans This study will assess the efficacy of acetylcysteine in patients undergoing surgery for otosclerosis
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| EudraCT 2006-006243-31 | None | None | None |