Ignite Creation Date:
2024-05-06 @ 6:24 PM
Last Modification Date:
2024-10-26 @ 2:47 PM
Study NCT ID:
NCT05655650
Status:
RECRUITING
Last Update Posted:
2022-12-19
First Post:
2022-12-09
Brief Title:
Identifying Biomarkers in Alzheimers Disease
Sponsor:
Chinese University of Hong Kong
Organization:
Chinese University of Hong Kong
Study Overview
Official Title:
Identifying Biomarkers in Alzheimers Disease
Status:
RECRUITING
Status Verified Date:
2022-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
SEEDS
Brief Summary:
Alzheimers disease is a severe neurodegenerative disorder of the brain that is characterized by progressive loss of memory and cognitive decline With the ageing population AD is a major public health problem affecting nearly 35 million people worldwide with numbers projected to rise to 1154 million by 2050 AD is the only cause of death among the top ten causes that has no prevention or cure It is believed that novel treatment of AD needs to start early or even at the prodromal stage in order to be effective Therefore there is an urgent need to find accurate methods of early detection before patients with AD develop clinical dementia
This study aims to identify biomarkers for AD in local Chinese population this study hypothesizes blood-based proteomics retinal imaging ASL-MRP and tau PET can improve the accuracy and staging of AD
This study aims to identify biomarkers for AD in local Chinese population this study hypothesizes blood-based proteomics retinal imaging ASL-MRP and tau PET can improve the accuracy and staging of AD
Detailed Description:
This is a cohort study It involves baseline and 6 yearly follow ups At baseline all participants will go through a list of cognitive assessments blood taking Brain MRI scan Brain PET scan and retinal imaging
At the first five yearly follow ups cognitive assessment will be performed For the sixth yearly follow up automatic retinal image will be performed in addition to cognitive assessment
At the first five yearly follow ups cognitive assessment will be performed For the sixth yearly follow up automatic retinal image will be performed in addition to cognitive assessment
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None