Ignite Creation Date:
2024-05-05 @ 6:39 PM
Last Modification Date:
2024-10-26 @ 9:35 AM
Study NCT ID:
NCT00521573
Status:
COMPLETED
Last Update Posted:
2007-08-28
First Post:
2007-08-27
Brief Title:
Effects of Chocolate on Coronary Vasomotion in Patients After Heart Transplantation
Sponsor:
University of Zurich
Organization:
University of Zurich
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2007-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of the present study is to investigate whether the ingestion of a flavonoid-rich dark chocolate compared to flavonoid-free placebo chocolate will improve coronary vasomotion in heart transplanted patients
Detailed Description:
Dark chocolate contains a high amount of flavonoids Flavonoids hold the possibilities to improve oxidative stress and hence the possibility to improve endothelium-dependent coronary vasomotion which is a powerful surrogate for clinical prognosis Coronary atherosclerosis is promoted by impaired endothelial function and increased platelet activation High oxidative stress and reduced antioxidant defenses play a crucial role in the pathogenesis of atherosclerosis in particular in transplanted hearts The aim of the present study is to investigate whether the ingestion of a flavonoid-rich dark chocolate compared to flavonoid-free placebo chocolate will improve coronary vasomotion in heart transplanted patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None