Ignite Creation Date:
2024-05-05 @ 6:39 PM
Last Modification Date:
2024-10-26 @ 9:36 AM
Study NCT ID:
NCT00526019
Status:
COMPLETED
Last Update Posted:
2012-02-22
First Post:
2007-09-05
Brief Title:
Persistence of Airway Inflammation and Remodeling in Subjects With Symptomatic or Complete Asthma Remission
Sponsor:
Laval University
Organization:
Laval University
Study Overview
Official Title:
Characteristics of Symptomatic Asthma Remissions
Status:
COMPLETED
Status Verified Date:
2012-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study aims at determining the patterns of asthma remission the prevalence of these different patterns the various factors associated with such remissions and possible recurrences of asthma in order to determine the mechanisms involved in these processes
The investigators therefore want to document these specificities in subjects in complete remission of their asthma and those in only symptomatic remission of their asthma in comparison with mildly symptomatic asthmatic subjects and healthy controls
The investigators therefore want to document these specificities in subjects in complete remission of their asthma and those in only symptomatic remission of their asthma in comparison with mildly symptomatic asthmatic subjects and healthy controls
Detailed Description:
Primary Outcome Measures
Airway inflammation induced sputum eosinophils
Secondary Outcome Measures
Perception of induced respiratory symptoms
Airway response to methacholine and AMP and perception scores
Diurnal variation in Peak Expiratory Flows
Profile of regulatory T cells in the peripheral blood
Changes in these parameters over time baseline 6 months 1 and 2 years
Airway inflammation induced sputum eosinophils
Secondary Outcome Measures
Perception of induced respiratory symptoms
Airway response to methacholine and AMP and perception scores
Diurnal variation in Peak Expiratory Flows
Profile of regulatory T cells in the peripheral blood
Changes in these parameters over time baseline 6 months 1 and 2 years
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None