Ignite Creation Date:
2024-05-06 @ 6:19 PM
Last Modification Date:
2024-10-26 @ 2:46 PM
Study NCT ID:
NCT05625503
Status:
RECRUITING
Last Update Posted:
2023-08-22
First Post:
2022-11-11
Brief Title:
Dilution of Verapamil During Intraarterial Administration
Sponsor:
University of Illinois at Chicago
Organization:
University of Illinois at Chicago
Study Overview
Official Title:
Does Dilution of Verapamil With Normal Saline or Blood Reduce Discomfort Felt During Intraarterial Administration
Status:
RECRUITING
Status Verified Date:
2023-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will be a randomized single-blind prospective trial designed to evaluate the efficacy and safety of intra-arterial IA Verapamil diluted with normal saline compared to undiluted IA Nicardipine during transradial access TRA for percutaneous coronary angiography Patients who are 18 years or older and undergoing non-emergent percutaneous coronary angiography via TRA will be included Patients who are non-English speaking pregnant or intubated will be excluded Patients will be randomized to one of the two following groups
1 Group 1 will receive IA Verapamil 5 mg 2mL diluted with 8 mL of normal saline
2 Group 2 will receive IA Nicardipine 400 mcg undiluted 8 mL
The investigators will document the patients level of discomfort on the Visual Analogue Scale 30 seconds before and after administration of IA VerapamilNicardipine The investigators will also document the presence of radial artery spasms
1 Group 1 will receive IA Verapamil 5 mg 2mL diluted with 8 mL of normal saline
2 Group 2 will receive IA Nicardipine 400 mcg undiluted 8 mL
The investigators will document the patients level of discomfort on the Visual Analogue Scale 30 seconds before and after administration of IA VerapamilNicardipine The investigators will also document the presence of radial artery spasms
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
True
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None