Ignite Creation Date:
2024-05-06 @ 6:18 PM
Last Modification Date:
2024-10-26 @ 2:45 PM
Study NCT ID:
NCT05616325
Status:
NOT_YET_RECRUITING
Last Update Posted:
2022-11-15
First Post:
2022-11-07
Brief Title:
Long-term Ovarian Fertility in Patients Treated for Lymphoma
Sponsor:
University Hospital Lille
Organization:
University Hospital Lille
Study Overview
Official Title:
Long-term Follow-up of Ovarian Function and Fertility in Young Lymphoma Patients Treated by Chemotherapy
Status:
NOT_YET_RECRUITING
Status Verified Date:
2022-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
FERTILymph
Brief Summary:
This is an observational single-center longitudinal cohort study In order to evaluate the gonadotoxicity of chemotherapy an AMH monitoring was initiated in 2006 in our fertility observatory in young patients with lymphoma before during and after chemotherapy This study is part of the project She will get better and then want a child and is supported by the ARS hauts de France n DOSSDESARFIR2019282 Our first study published in 2010 shows that AMH decreases sharply during chemotherapy regardless of the chemotherapy protocol At the end of chemotherapy AMH recovery profiles differ according to the protocol received This follow-up is therefore essential in order to adapt our practices and our preservation strategies particularly to the type of chemotherapy Patients are primarily concerned about their chances of subsequent pregnancy and there is little evidence in the literature about the impact of chemotherapy on ovarian reserve and long-term fertility
The fisrt objective of our study is to evaluate at distance from chemotherapy the evolution of ovarian function in patients treated for lymphoma by evaluating follicular reserve parameters AMH and antral follicle count at 5 and 10 years after the end of chemotherapy compared with the initial workup performed before chemotherapy and the workup performed at 12 months after the end of chemotherapy
The fisrt objective of our study is to evaluate at distance from chemotherapy the evolution of ovarian function in patients treated for lymphoma by evaluating follicular reserve parameters AMH and antral follicle count at 5 and 10 years after the end of chemotherapy compared with the initial workup performed before chemotherapy and the workup performed at 12 months after the end of chemotherapy
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 2022-A01753-40 | OTHER | ID-RCB number ANSM | None |