Ignite Creation Date:
2024-05-05 @ 6:38 PM
Last Modification Date:
2024-10-26 @ 9:35 AM
Study NCT ID:
NCT00517478
Status:
UNKNOWN
Last Update Posted:
2007-08-17
First Post:
2007-08-15
Brief Title:
Thromboelastography As A Tool for Possible Clopidogrel Resistance in The Patients Treated With Primary PCI for STEMI
Sponsor:
Assaf-Harofeh Medical Center
Organization:
Assaf-Harofeh Medical Center
Study Overview
Official Title:
None
Status:
UNKNOWN
Status Verified Date:
2007-07
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Determine usefulness of thromboelastography TEG as a valuable tool in ex-vivo assessing platelet response to aspirin and clopidogrel dual treatment and on-treatment platelet reactivity during acute ST segment elevation myocardial infarction STEMI in an acute phase during primary PCI PPCI and also during recovery been on maintenance medical therapy and to determine the correlation between platelet response to clopidogrel treatment and the outcome of patients
Detailed Description:
Dual anti-aggregant therapy is recommended standard of therapy applicable to all patient groups undergoing PPCI The aspirin-clopidogrel regiment is signed to every patient without assessing therapeutic effect In face of growing evidence of platelet resistance to the standardized therapy there is a demand for reliable diagnostic tool for rapid and accurate assessment of platelet reactivity TEG is an established technique to assess the quality of clot formation used mainly in surgery and obstetrics to determine possible bleeding diathesis Recently it became to be used in cardiology where it can be a valuable tool to assess a response to antiplatelet therapy and its association with the outcome However there is a few data about use of TEG in STEMI patients undergoing PCI Our study is designed to assess by TEG the platelets response to clopidogrel treatment during acute STEMI in patients undergoing primary PCI and the correlation of this response with the long term outcome
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None