Ignite Creation Date:
2024-05-06 @ 6:15 PM
Last Modification Date:
2024-10-26 @ 2:45 PM
Study NCT ID:
NCT05607654
Status:
RECRUITING
Last Update Posted:
2023-01-13
First Post:
2022-10-26
Brief Title:
The Mechanisms of Underlying Accelerated Repetitive Transcranial Magnetic Stimulation for Treatment-resistant Depression
Sponsor:
First Affiliated Hospital of Zhejiang University
Organization:
First Affiliated Hospital of Zhejiang University
Study Overview
Official Title:
The Mechanisms of Underlying Accelerated Repetitive Transcranial Magnetic Stimulation for Treatment-resistant Depression Via Reelin-Apoer2-NMDAR Pathway- Mediated Synaptic Plasticity
Status:
RECRUITING
Status Verified Date:
2022-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In this project the investigators evaluate an accelerated schedule of repetitive transcranial magnetic stimulation for treatment-resistant depression The investigators focuse on participants brain activity and blood markers Reelin Apoer2 NMDAR BDNF exosomes and so on to deepen the understanding of the mechanism of accelerated rTMS for treatment-resistant depression
Detailed Description:
In this project the investigator evaluate an accelerated schedule of repetitive transcranial magnetic stimulation for treatment-resistant depression Patients were included in two groups and received an accelerated stimulation or sham treatment The changes of neuroimaging and biomarkers at baseline 5 days after treatment and 1 month after treatment are evaluated The investigators focuse on participants brain activity and blood markers Reelin Apoer2 NMDAR BDNF exosomes and so on to deepen the understanding of the mechanism of accelerated rTMS for treatment-resistant depression
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None