Ignite Creation Date:
2025-12-24 @ 6:52 PM
Ignite Modification Date:
2025-12-29 @ 5:25 PM
Study NCT ID:
NCT04218357
Status:
COMPLETED
Last Update Posted:
2025-02-27
First Post:
2020-01-01
Is NOT Gene Therapy:
True
Has Adverse Events:
True
Brief Title:
Probenecid as Medication for Alcohol Use Disorder (PROB)
Sponsor:
Brown University
Organization:
Study Overview
Official Title:
Probenecid as Pharmacotherapy for Alcohol Use Disorder
Status:
COMPLETED
Status Verified Date:
2025-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PROB
Brief Summary:
The design is a randomized, within-subject, crossover, double-blind, placebo-controlled human alcohol laboratory study with one oral dose of 2g probenecid or placebo administered in two laboratory sessions.
Detailed Description:
There will be a total of four study visits. Visit 1 is the screening for eligibility (medical and physical examination). On Visits 2 and 3, participants will undergo an alcohol laboratory session with a one week washout period before administering the alternate therapy. The study will conclude at Visit 4.
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
True
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
True
Is an FDA AA801 Violation?: