Ignite Creation Date:
2024-05-06 @ 6:15 PM
Last Modification Date:
2024-10-26 @ 2:44 PM
Study NCT ID:
NCT05591599
Status:
RECRUITING
Last Update Posted:
2023-03-16
First Post:
2022-10-17
Brief Title:
Diagnostic Value of Calponin 2 in Identifying Tubal Pregnancies
Sponsor:
Mỹ Đức Hospital
Organization:
Mỹ Đức Hospital
Study Overview
Official Title:
Diagnostic Value of Calponin 2 in Identifying Tubal Pregnancies
Status:
RECRUITING
Status Verified Date:
2022-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
CNN2
Brief Summary:
Ectopic pregnancy EP is the implantation of a fertilized egg outside the main cavity of the uterus EP is one of the most common gynecologic surgical emergencies and one of leading causes of maternal mortality in the first trimester of pregnancy Embryo implantation exerts different pressure on uterine and tubal epithelial and smooth muscle cells calponin 2 CNN2 expression at the implantation site would differ between intrauterine pregnancy and tubal pregnancy The investigators conduct this study to find out the diagnostic value of CNN2 in identifying tubal pregnancies
Detailed Description:
This is a case-control prospective study Women age 18-35 years old come to My Duc My Duc phu Nhuan Hospital and Ngoc Lan Clinic and have the indication of testing beta human chorionic gonadotropin hCG for determining pregnancy status because of 1-14 days period delay with or without abdominal pain vaginal bleeding or after assisted reproductive technology Those women will be introduced about the study If they agree to take part in and write the consent form they will be taken 5ml of blood more at the same time of testing beta hCG Blood sample will then be centrifuged and collected serum will then be stored at -80 celsius degree
Women with negative beta hCG will be excluded Women with positive beta hCG will be followed-up pregnancy as routine until 12 67 weeks of gestational age GA At this time those women will be screened using including and excluding criteria for each group They then be put group into 1 tubal pregnancy 2 viable pregnancy and 3 early pregnancy loss
Stored serum sample will be defrosted and measured CNN2 concentration
Women with negative beta hCG will be excluded Women with positive beta hCG will be followed-up pregnancy as routine until 12 67 weeks of gestational age GA At this time those women will be screened using including and excluding criteria for each group They then be put group into 1 tubal pregnancy 2 viable pregnancy and 3 early pregnancy loss
Stored serum sample will be defrosted and measured CNN2 concentration
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None