Ignite Creation Date:
2024-05-05 @ 6:37 PM
Last Modification Date:
2024-10-26 @ 9:35 AM
Study NCT ID:
NCT00511251
Status:
COMPLETED
Last Update Posted:
2007-08-03
First Post:
2007-08-02
Brief Title:
Analysis of Induced Sputum and Lung Biopsies by SEM a Tool to Identify Source of Exposure of Workers to Hazardous Dust
Sponsor:
Tel-Aviv Sourasky Medical Center
Organization:
Tel-Aviv Sourasky Medical Center
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2007-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Aim to validate the qualitative analysis by Scanning Electron Microscope SEM of lung samples first in induced sputum in correlation to disease second by comparing hazardous particles in induced sputum to the analysis in lung tissue and finally by assessing if the particles present in transplanted patients correlated with occupational history
Detailed Description:
Abstract
Background On the last few years there is a rise in the public awareness of the danger potential that lies in the exposure to hazardous dust in different professions The examination of induced sputum has been used from the early eighties to research and diagnose inflammatory lung diseases We assess here patients with lung disease and occupational history in order to undergo work up to assess hazardous dust exposure
Aim to validate the qualitative analysis by Scanning Electron Microscope SEM of lung samples first in induced sputum in correlation to disease second by comparing hazardous particles in induced sputum to the analysis in lung tissue and finally by assessing if the particles present in transplanted patients correlated with occupational history
Methods 40 patients referred with occupational history were included For 24 of them SEM analysis was done in induced sputum IS together with questionnaires and in 11 among them the SEM analysis was done both from lung tissue TS and IS In addition 11 lung biopsies from patients with occupational history were scanned by SEM and compared to 10 biopsies from patients with no occupational history
Background On the last few years there is a rise in the public awareness of the danger potential that lies in the exposure to hazardous dust in different professions The examination of induced sputum has been used from the early eighties to research and diagnose inflammatory lung diseases We assess here patients with lung disease and occupational history in order to undergo work up to assess hazardous dust exposure
Aim to validate the qualitative analysis by Scanning Electron Microscope SEM of lung samples first in induced sputum in correlation to disease second by comparing hazardous particles in induced sputum to the analysis in lung tissue and finally by assessing if the particles present in transplanted patients correlated with occupational history
Methods 40 patients referred with occupational history were included For 24 of them SEM analysis was done in induced sputum IS together with questionnaires and in 11 among them the SEM analysis was done both from lung tissue TS and IS In addition 11 lung biopsies from patients with occupational history were scanned by SEM and compared to 10 biopsies from patients with no occupational history
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None