Ignite Creation Date:
2024-05-06 @ 6:12 PM
Last Modification Date:
2024-10-26 @ 2:44 PM
Study NCT ID:
NCT05586828
Status:
COMPLETED
Last Update Posted:
2023-04-20
First Post:
2022-10-17
Brief Title:
A Single-center Retrospective Cohort Study to Explore the Prognostic Significance of CONUT in Elderly CAD Patients With HFpEFand Compare CONUT With Other Objective Nutritional Indices
Sponsor:
Beijing Tongren Hospital
Organization:
Beijing Tongren Hospital
Study Overview
Official Title:
A Single-center Retrospective Cohort Study to Explore the Prognostic Significance of CONUT in Elderly With HFpEF and Compare Controlling Nutritional Status Score With Other Objective Nutritional Indices The Primary Endpoint of This Study Was Readmission Due to HF and All-cause Mortality in 1 Year After Hospitalization
Status:
COMPLETED
Status Verified Date:
2022-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
HF is an advanced or terminal stage of various heart diseases with high rehospitalization and mortality rates In HF patients undernutrition is not uncommon and represents one of the most significant determinants of poor clinical outcomes Therefore nutritional management is of paramount importance for patients with HFThe basic method of nutritional management is to effectively identify the nutritional status of patients with heart failure especially in elderly patients with heart failure who are not easy to find in the early stage Limited data are available regarding the association between CONUT score and prognosis in elder patients with HFpEF despite its easy availability in routine blood chemistry Therefore we aimed to evaluate the prognostic significance of CONUT score and to compare it with other well-established nutritional indices in HFpEF a common HF phenotype in the elderly population with coronary artery disease
This was a single-center retrospective cohort study which were approved by the Clinical Research Ethics Committee of our hospital TRECKY2021-185 Written informed consent was obtained from all patients
Participants were accorded with diagnostic criteria of CAD and HFpEF excluding rheumatic heart disease congenital heart disease acute myocardial infarction hemodialysis or hemofiltration tumour activity urgent surgery death during hospitalization HF of unknown reasons New York Heart AssociationNYHA class1and data deficiency Demographic characteristics and medical parameters were collected from the electronic medical record system All enrolled patients were followed-up in an outpatients setting The primary endpoint of this study was readmission due to heart failure and all-cause mortality in the first year after hospitalization To explore the prognostic significance of controlling nutritional status score in elderly with ejection fraction preserved heart failure and compare controlling nutritional status score with other objective nutritional indicesAll analyses were performed using Statistical Product Service SolutionsSPSS version 190
This was a single-center retrospective cohort study which were approved by the Clinical Research Ethics Committee of our hospital TRECKY2021-185 Written informed consent was obtained from all patients
Participants were accorded with diagnostic criteria of CAD and HFpEF excluding rheumatic heart disease congenital heart disease acute myocardial infarction hemodialysis or hemofiltration tumour activity urgent surgery death during hospitalization HF of unknown reasons New York Heart AssociationNYHA class1and data deficiency Demographic characteristics and medical parameters were collected from the electronic medical record system All enrolled patients were followed-up in an outpatients setting The primary endpoint of this study was readmission due to heart failure and all-cause mortality in the first year after hospitalization To explore the prognostic significance of controlling nutritional status score in elderly with ejection fraction preserved heart failure and compare controlling nutritional status score with other objective nutritional indicesAll analyses were performed using Statistical Product Service SolutionsSPSS version 190
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None