Ignite Creation Date:
2024-05-05 @ 6:36 PM
Last Modification Date:
2024-10-26 @ 9:35 AM
Study NCT ID:
NCT00519337
Status:
COMPLETED
Last Update Posted:
2012-01-05
First Post:
2007-08-20
Brief Title:
Impact of Ascorbic Acid on Post-Cardiothoracic Surgery Inflammation
Sponsor:
Hartford Hospital
Organization:
Hartford Hospital
Study Overview
Official Title:
The Impact of Ascorbic Acid Therapy on Inflammatory Mediators in Cardiothoracic Surgery Patients The Atrial Fibrillation Suppression Trial IV AFIST IV Pilot Study
Status:
COMPLETED
Status Verified Date:
2012-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
AFIST
Brief Summary:
The purpose of this study is to see if ascorbic acid Vitamin-C therapy will reduce inflammation following heart surgery
Detailed Description:
Atrial Fibrillation is a significant cause of morbidity following cardiothoracic surgery Despite prophylactic therapy with beta-blockers and amiodarone post-operative atrial fibrillation occurs in approximately 22 of patients We believe that by reducing the inflammation that is caused during CTS we can see further improvements without any negative effects on hemodynamics Ascorbic acid a free radical scavenger has been found to lower inflammation mediators but never in a CTS population This study will help determine the affect of ascorbic acid on the inflammation associated with CTS
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None