Ignite Creation Date:
2024-05-06 @ 6:03 PM
Last Modification Date:
2024-10-26 @ 2:41 PM
Study NCT ID:
NCT05533606
Status:
COMPLETED
Last Update Posted:
2023-11-18
First Post:
2022-09-02
Brief Title:
Risk Factors and Machine Learning Model for Beta-Lactam Drugs Related Acute Kidney Injury
Sponsor:
Qianfoshan Hospital
Organization:
Qianfoshan Hospital
Study Overview
Official Title:
Analysis of Risk Factors of Beta-Lactam Drugs Related Acute Kidney Injury in Hospitalized Patients and Developments of Machine Learning Model
Status:
COMPLETED
Status Verified Date:
2023-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Acute kidney injury AKI also known as acute kidney failure ARF is a common and complex kidney disease in clinic and an important factor related to poor prognosis of patients in clinic In the present study a single-center retrospective study was conducted in our center The clinical data of hospitalized patients received β-Lactam drugs from January 2018 to December 2020 was retrospectively analyzed The multiple logistic regression analysis suggested that complicated with hypertension anemia pneumonia shock sepsis heart failure combined use of proton pump inhibitors PPI angiotensin-converting enzyme inhibitor ACEI angiotensin Ⅱ receptor antagonist ARB were independent risk factors for AKI related to β-Lactam drugs In clinical practice patients with acute kidney injury risk factors should be closely monitored for changes in their blood creatinine and urine output to avoid acute kidney injury For patients who have suffered from acute kidney injury the cause should be removed in time and corresponding symptomatic treatment should be given
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None