Ignite Creation Date:
2024-05-06 @ 6:02 PM
Last Modification Date:
2024-10-26 @ 2:40 PM
Study NCT ID:
NCT05526131
Status:
COMPLETED
Last Update Posted:
2022-09-02
First Post:
2022-08-31
Brief Title:
BDNF Level and val66met Polymorphism of Brain Derived Neurotropic Factor Gene in Patients With T2DM and Depression
Sponsor:
Kasr El Aini Hospital
Organization:
Kasr El Aini Hospital
Study Overview
Official Title:
Brain Derived Neurotropic Factor Level and val66met Polymorphism of Brain Derived Neurotropic Factor Gene in Patients With Type Two Diabetes Mellitus and Depression
Status:
COMPLETED
Status Verified Date:
2022-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study aimed to evaluate the relation between the levels of Brain Derived Neurotropic Factor BDNF and val66met polymorphism of BDNF gene and the presence of depression in type 2 diabetes In addition to studying the relationship between BDNF level and val66met polymorphism of its gene and assessing relation between BDNF level and obesity
Detailed Description:
The study included 88 type 2 diabetic patients which are further divided into two groups depressed and non-depressed Depression was assessed by Hamilton Depression Rating Scale HAM-D and structured clinical interview for DSM-IV Axis disorder SCID-I for diagnosing depression and exclusion of other psychiatric disorders Genotyping was performed by using Real Time-PCR TaqMan probes
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None