Ignite Creation Date:
2024-05-05 @ 6:34 PM
Last Modification Date:
2024-10-26 @ 9:34 AM
Study NCT ID:
NCT00504049
Status:
COMPLETED
Last Update Posted:
2010-07-22
First Post:
2007-07-17
Brief Title:
Wavelet Analysis of Electromyography EMG in Cerebral Palsy
Sponsor:
Shriners Hospitals for Children
Organization:
Shriners Hospitals for Children
Study Overview
Official Title:
Wavelet Analysis of Surface EMG in Cerebral Palsy
Status:
COMPLETED
Status Verified Date:
2009-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Several methods exist to evaluate motor function in the child with cerebral palsy and are used to assess the outcome of a clinical intervention However these scales are not directed towards measuring the changes in muscle activity patterns that can result from the intervention For example there are classification scales aimed at measuring motor function and functional abilities and indices of gait function These scores while providing a way to quantify function and mechanics do not directly measure muscle activation characteristics Therefore these tests may be insensitive to how the intervention has directly affected muscle function which is usually the focus of the intervention ie botulinum toxin functional electrical stimulation dorsal rhizotomy Muscle biopsies and motor evoked potentials can provide information about the muscle activation characteristics however they are invasive and there are concerns about using these techniques on the pediatric population andor the practicality of clinical implementation especially since they do not provide insight into how the muscle behaves during a functional task One method that can be used to provide insight into muscle activity in a non-invasive and clinically meaningful manner is the use of surface electromyography sEMG Surface EMG is typically a routine part of clinical assessment and the evaluation of motor impairment in CP However the analysis of the data has been limited in most cases to examination of signal amplitude or differences in muscle onset and offset timing
The long-term goal of this research is to develop an analysis method for sEMG that can be used during functional tasks for treatment planning diagnostic assessment purposes in CP This is to be accomplished through the use of the continuous wavelet transform CWT By developing an assessment method based on muscle activity it is believed that a clinically viable measurement tool can be devised that will provide a level of insight into the effects of an intervention on muscle pathophysiology that is not currently available The first step in progressing towards this long-term goal is to determine the variability and range of expected time-frequency patterns that can be expressed in a given population ie cerebral palsy during the execution of a meaningful task gait and relate the time-frequency information back to more standard assessments
The long-term goal of this research is to develop an analysis method for sEMG that can be used during functional tasks for treatment planning diagnostic assessment purposes in CP This is to be accomplished through the use of the continuous wavelet transform CWT By developing an assessment method based on muscle activity it is believed that a clinically viable measurement tool can be devised that will provide a level of insight into the effects of an intervention on muscle pathophysiology that is not currently available The first step in progressing towards this long-term goal is to determine the variability and range of expected time-frequency patterns that can be expressed in a given population ie cerebral palsy during the execution of a meaningful task gait and relate the time-frequency information back to more standard assessments
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None