Ignite Creation Date:
2024-05-06 @ 5:57 PM
Last Modification Date:
2024-10-26 @ 2:39 PM
Study NCT ID:
NCT05494658
Status:
RECRUITING
Last Update Posted:
2024-03-25
First Post:
2022-07-26
Brief Title:
Impact of Preoperative Oral Branched-chain Amino Acids on Reducing Postoperative Insulin Resistance
Sponsor:
Sun Peng
Organization:
Shanghai Tong Ren Hospital
Study Overview
Official Title:
A Multicenter Randomized Controlled Study of Preoperative Oral Administration of Branched-chain Amino Acids in Reducing Postoperative Insulin Resistance in Colorectal Cancer Patients
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Postoperative insulin resistance refers to the phenomenon that the bodys glucose uptake stimulated by insulin is reduced due to stress effects such as trauma or the inhibitory effect of insulin on liver glucose output is weakened after surgery
There is a clear link between postoperative insulin resistance and poor perioperative prognosis Therefore exploring interventions to reduce postoperative stress insulin resistance stabilize postoperative blood glucose and reduce postoperative complications are clinical problems that need to be solved urgently In recent years research on branched-chain amino acids and metabolic diseases has become a hot spot Studies have found that in the rat model preoperatively given a high branched-chain amino acid diet can inhibit postoperative insulin resistance and stabilize blood glucose levels This research plan is to try to add branched-chain amino acids before surgery to observe the occurrence of postoperative insulin resistance in patients
There is a clear link between postoperative insulin resistance and poor perioperative prognosis Therefore exploring interventions to reduce postoperative stress insulin resistance stabilize postoperative blood glucose and reduce postoperative complications are clinical problems that need to be solved urgently In recent years research on branched-chain amino acids and metabolic diseases has become a hot spot Studies have found that in the rat model preoperatively given a high branched-chain amino acid diet can inhibit postoperative insulin resistance and stabilize blood glucose levels This research plan is to try to add branched-chain amino acids before surgery to observe the occurrence of postoperative insulin resistance in patients
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None