Ignite Creation Date:
2024-05-05 @ 6:34 PM
Last Modification Date:
2024-10-26 @ 9:34 AM
Study NCT ID:
NCT00503594
Status:
UNKNOWN
Last Update Posted:
2012-07-30
First Post:
2007-07-18
Brief Title:
Methotrexate and Temozolomide Versus Methotrexate Procarbazine Vincristine and Cytarabine
Sponsor:
Assistance Publique - Hôpitaux de Paris
Organization:
Assistance Publique - Hôpitaux de Paris
Study Overview
Official Title:
Multicenter Randomized Phase II Study of Methotrexate MTX and Temozolomide Versus MTX Procarbazine Vincristine and Cytarabine for Primary CNS Lymphoma PCNSL in the Elderly
Status:
UNKNOWN
Status Verified Date:
2007-07
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
CNSLymphoma
Brief Summary:
The purpose of this study is to evaluate two types of chemotherapy for primary central nervous system lymphoma in the elderly age older than 60
Methotrexate procarbazine vincristine and cytarabine
Methotrexate and temozolomide
Methotrexate procarbazine vincristine and cytarabine
Methotrexate and temozolomide
Detailed Description:
The aim of the study is to evaluate efficacy and toxicity associated with both protocols in this population without radiotherapy
Patients will be randomized to receive one of the two regimens in one of the participating centers Neuropsychological evaluation will be performed in all patients Patients will be followed with serial MRIs
Patients will be randomized to receive one of the two regimens in one of the participating centers Neuropsychological evaluation will be performed in all patients Patients will be followed with serial MRIs
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None