Ignite Creation Date:
2024-05-05 @ 6:34 PM
Last Modification Date:
2024-10-26 @ 9:35 AM
Study NCT ID:
NCT00509678
Status:
COMPLETED
Last Update Posted:
2012-01-18
First Post:
2007-07-27
Brief Title:
Rituxan With or Without Methotrexate in Psoriatic Arthritis
Sponsor:
Swedish Medical Center
Organization:
Swedish Medical Center
Study Overview
Official Title:
Phase IB Investigator-Initiated Open-Label Multi-Center Trial of Rituximab With or Without Methotrexate In Subjects With Psoriatic Arthritis and Psoriasis
Status:
COMPLETED
Status Verified Date:
2012-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to help determine the effectiveness of rituxan with or without methotrexate in the treatment of psoriatic arthritis
Detailed Description:
The purpose of this study is to evaluate safety and efficacy of rituximab with and without methotrexate in joints enthesium and skin in psoriatic arthritis patients with inadequate response to methotrexate who have either not tried anti-TNF therapy or have had inadequate or failed response to anti-TNF therapy To explore biologic mechanism of action via histological and immunohistochemical evaluation of pre and post treatment biopsies of psoriatic plaques
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None