Ignite Creation Date:
2024-05-06 @ 5:51 PM
Last Modification Date:
2024-10-26 @ 2:36 PM
Study NCT ID:
NCT05453760
Status:
RECRUITING
Last Update Posted:
2023-12-07
First Post:
2022-07-07
Brief Title:
Lung Ultrasound in the Early Detection of Postoperative Pulmonary Complications After Esophagectomy
Sponsor:
University Hospital Lille
Organization:
University Hospital Lille
Study Overview
Official Title:
Lung Ultrasound in the Early Detection of Postoperative Pulmonary Complications After Esophagectomy A Prospective Observational Study
Status:
RECRUITING
Status Verified Date:
2023-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
OESOLUS
Brief Summary:
The perioperative management of esophageal cancer has evolved considerably in recent years
Over the last 30 years postoperative mortality has been steadily decreasing However respiratory morbidity remains high 30-40 This is due to the procedure itself requiring a thoracic approach and intraoperative unipulmonary ventilation The postoperative pulmonary complications PPCs are multiple bronchial congestion atelectasis pneumopathy acute respiratory distress syndrome ARDS liquid pleural effusion pneumothorax
In general prevention and early treatment are aimed at limiting the evolution towards acute respiratory failure requiring ventilatory assistance
Chest radiography is essential for the presumptive diagnosis of pneumopathy in particular but the interpretation of the images may be difficult
Thoracic computed tomography CT is the gold standard because it is sensitive and can discriminate among differential diagnoses This is difficult to perform it requires intra-hospital transport of patient who is often in acute respiratory failure and the availability of an examination area
Lung ultrasound is used at the bedside for diagnosis of lung infection in intensive care unit This has a sensitivity close to thoracic CT and has the advantage of being feasible at any time does not require transport of the patient and is not irradiating
Lung ultrasound allows early detection of the need for ventilatory support in postoperative major abdominal surgery In addition the sensitivity of lung ultrasound is close to that of CT allowing this examination to be relied upon
The main objective of the study is to determine the role of lung ultrasound in the prediction of postoperative pulmonary complications within one hour after extubation
Over the last 30 years postoperative mortality has been steadily decreasing However respiratory morbidity remains high 30-40 This is due to the procedure itself requiring a thoracic approach and intraoperative unipulmonary ventilation The postoperative pulmonary complications PPCs are multiple bronchial congestion atelectasis pneumopathy acute respiratory distress syndrome ARDS liquid pleural effusion pneumothorax
In general prevention and early treatment are aimed at limiting the evolution towards acute respiratory failure requiring ventilatory assistance
Chest radiography is essential for the presumptive diagnosis of pneumopathy in particular but the interpretation of the images may be difficult
Thoracic computed tomography CT is the gold standard because it is sensitive and can discriminate among differential diagnoses This is difficult to perform it requires intra-hospital transport of patient who is often in acute respiratory failure and the availability of an examination area
Lung ultrasound is used at the bedside for diagnosis of lung infection in intensive care unit This has a sensitivity close to thoracic CT and has the advantage of being feasible at any time does not require transport of the patient and is not irradiating
Lung ultrasound allows early detection of the need for ventilatory support in postoperative major abdominal surgery In addition the sensitivity of lung ultrasound is close to that of CT allowing this examination to be relied upon
The main objective of the study is to determine the role of lung ultrasound in the prediction of postoperative pulmonary complications within one hour after extubation
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 2022-A00655-38 | OTHER | ID-RCB number ANSM | None |