Ignite Creation Date:
2024-05-06 @ 5:50 PM
Last Modification Date:
2024-10-26 @ 2:36 PM
Study NCT ID:
NCT05447390
Status:
UNKNOWN
Last Update Posted:
2022-07-07
First Post:
2022-06-28
Brief Title:
Evaluation of the Strength of Handgrip in Patients With Pulmonary Artery Hypertension
Sponsor:
Gazi University
Organization:
Gazi University
Study Overview
Official Title:
Evaluation of the Strength of Handgrip in Patients With Pulmonary Artery Hypertension
Status:
UNKNOWN
Status Verified Date:
2022-07
Last Known Status:
ACTIVE_NOT_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Our study aims to investigate the changes in muscle strength and muscle mass in PAH patients compared to healthy individuals and determine its effects on prognosis
Further categorization of PAH patients based on their NYHA class will help determine if their handgrip strength decreases while progressing from NYHA class 1 to 4 This in turn allows us to examine if the handgrip test can be considered as an alternative to a 6-minute walking test 6MWT
The Jamar Hydraulic Hand Dynamometer device in our hospital is used for measuring the handgrip strength test
The data of the included subjects in this study are obtained and recorded from the existing files Also the handgrip strength test data will be recorded after the investigation
Further categorization of PAH patients based on their NYHA class will help determine if their handgrip strength decreases while progressing from NYHA class 1 to 4 This in turn allows us to examine if the handgrip test can be considered as an alternative to a 6-minute walking test 6MWT
The Jamar Hydraulic Hand Dynamometer device in our hospital is used for measuring the handgrip strength test
The data of the included subjects in this study are obtained and recorded from the existing files Also the handgrip strength test data will be recorded after the investigation
Detailed Description:
In our study dynamometer tests will be applied to approximately 15 patients diagnosed with PAH For control purposes a hand dynamometer test will be applied to 40 healthy children Patients age gender weight height NYHA class used medications complete blood count Hb Hct MCV RDW BNP Troponin-t biochemical parameters catheterization findings at diagnosis Echocardiographic findings Tricuspid Annular Plane Systolic Excursion-TAPSE Right Ventricular End Systolic Remodeling Index RVES-RI Pulmonary Artery acceleration Time PAaccT Tricuspid Velocity Time Integral TR-VTI RV area RV length Right Ventricular Load Adaptation Index RV LAI congenital heart disease and whether there is a shunt recorded or not Patients are informed about the test before the dynamometer test This may affect the integrity and accuracy of test results To prevent such inaccuracies the test will be performed on patients both hands and the results are not recorded Patients are asked to sit in a specific position That is to sit upright with their elbows flexed 90 and the palms facing inwards medially Then the test is performed 3 times with both hands The results are recorded as the average of all the trials for dominant and non-dominant hands separately The length of patients hands is also measured With the help of this testit is possible to measure the difference in handgrip strength between healthy subjects and PAH patients Additionally patients are divided into 4 groups based on their NYHA classes This will investigate if the patients handgrip strength decreases as progress from NYHA class 1 to 4
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None