Ignite Creation Date:
2024-05-05 @ 6:32 PM
Last Modification Date:
2024-10-26 @ 9:34 AM
Study NCT ID:
NCT00500825
Status:
COMPLETED
Last Update Posted:
2008-05-16
First Post:
2007-07-11
Brief Title:
Influence of Therapeutic Hypothermia on Resting Energy Expenditure
Sponsor:
Medical University of Vienna
Organization:
Medical University of Vienna
Study Overview
Official Title:
Influence of Therapeutic Hypothermia on Resting Energy Expenditure in Patients After Cardiopulmonary Resuscitation
Status:
COMPLETED
Status Verified Date:
2008-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is the evaluation of the influence of therapeutic hypothermia on resting energy expenditure REE in patients after cardiopulmonary resuscitation CPR We hypothesized that hypothermia would reduce resting energy expenditure in these patients
Detailed Description:
Therapeutic hypothermia improves neurologic outcome in patients after cardiopulmonary resuscitation CPR because of cardiac arrest In the present study patients will be cooled to 33 degree Celsius after CPR for 24h To avoid shivering patients will be analgosedated and medically paralysed Analgosedation and relaxation have already shown to reduce oxygen consumption up to 20 in critically ill patients
In patients with brain injury who were cooled to 33 degree Celsius using a cooling meadow REE could be significantly reduced In critically ill patients with pyrexia cooling using a cooling meadow REE could be reduced Oxygen consumption was reduced about 147 per degree Celsius
So far no studies evaluating influence of therapeutic hypothermia on REE in patients after CPR have been published Therefore we plan to measure REE in 25 cooled patients after CPR using indirect Calorimetry Deltatrac II Metabolic Monitor Datex Instrumentarium Helsinki Finland
In patients with brain injury who were cooled to 33 degree Celsius using a cooling meadow REE could be significantly reduced In critically ill patients with pyrexia cooling using a cooling meadow REE could be reduced Oxygen consumption was reduced about 147 per degree Celsius
So far no studies evaluating influence of therapeutic hypothermia on REE in patients after CPR have been published Therefore we plan to measure REE in 25 cooled patients after CPR using indirect Calorimetry Deltatrac II Metabolic Monitor Datex Instrumentarium Helsinki Finland
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None