Ignite Creation Date:
2024-05-06 @ 5:48 PM
Last Modification Date:
2024-10-26 @ 2:36 PM
Study NCT ID:
NCT05439317
Status:
COMPLETED
Last Update Posted:
2023-02-22
First Post:
2022-05-19
Brief Title:
Elasticity of the Hoffas Fat Pad in Patients With Knee Osteoarthritis
Sponsor:
Taipei Veterans General Hospital Taiwan
Organization:
Taipei Veterans General Hospital Taiwan
Study Overview
Official Title:
Elasticity of the Hoffas Fat Pad in Patients With Knee Osteoarthritis
Status:
COMPLETED
Status Verified Date:
2023-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Knee osteoarthritis OA is a common problem in clinical settings Knee OA is well known for its association with the wear and tear of the cartilage and osteophyte formation Evidence has suggested the importance of the infrapatellar fat pad known as Hoffas fat pad during the development of knee OA Some studies have demonstrated the protective role of the infrapatellar fat pad whereas others have suggested an inflammatory role such as increased fibrosis and proinflammatory cytokine levels Ultrasound is exceptionally convenient in the assessment of the musculoskeletal system and elastography is a tool to evaluate tissue texture Therefore in this study we investigated the Hoffas fat pad in knee OA patients by using elastography
Detailed Description:
This was an observation study that included a control group We enrolled 20 patients with knee OA as well as 10 healthy individuals The Western Ontario and McMaster Universities Osteoarthritis Index WOMAC and Kellgren-Lawrence X-ray grading were employed to determine disease severity All the study participants received elastography assessment including strain and shear wave elastography in the knee extension and flexion position The strain elastography contained color mapping that enabled the calculation of the relative texture and strain ratio The shear wave elastography revealed the qualitative velocity which was measured 3 times Each patients with knee OA received elastography examination twice once before hyaluronic acid injection and once 1 month after the injection
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None