Ignite Creation Date:
2024-05-05 @ 6:32 PM
Last Modification Date:
2024-10-26 @ 9:34 AM
Study NCT ID:
NCT00494975
Status:
COMPLETED
Last Update Posted:
2011-01-27
First Post:
2007-06-29
Brief Title:
The Effect of Phototherapy on Pruritus of Patients With Chronic Kidney Disease
Sponsor:
National Taiwan University Hospital
Organization:
National Taiwan University Hospital
Study Overview
Official Title:
The Effect of Phototherapy on Pruritus of Patients With Chronic Kidney Disease
Status:
COMPLETED
Status Verified Date:
2010-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study was to confirm the efficacy of NB UVB phototherapy in alleviating uremic pruritus and investigate the association between improvement of pruritus and change of serum parameters including routine biochemical data immune profile and dialysis adequacy
Detailed Description:
We would conduct a randomized study to evaluate the effect of NB UVB therapy on uremic pruritus The intensity of pruritus will be evaluated using visual analog scale VAS score 0 no pruritus-10 most severe pruritus and a detailed questionnaire assessing various characteristics of pruritus at baseline The patients with the intensity of pruritus VAS score more than 5 will be randomized to narrow band UVB and control group Phototherapy was administered to the whole body surface 2-3 sessions per week for total 18 sessions in a UV irradiation cubicle The dose increased from 210mJcm2 Doses were increased by 10 at every session The control group received time-matched exposures to long-wave ultraviolet light The investigator will determine the pruritic intensity at baseline every 3 sessions by VAS score and by detailed questionnaire at baseline and after 18 sessions The blood sample will also be collected at baseline and after treatment to determine factors associated with improvement
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None