Ignite Creation Date:
2024-05-05 @ 11:20 AM
Last Modification Date:
2024-10-26 @ 9:04 AM
Study NCT ID:
NCT00004572
Status:
UNKNOWN
Last Update Posted:
2005-06-24
First Post:
2000-02-16
Brief Title:
Identification and Therapy Efficacy of Type 2 Diabetes in Hispanic Patients
Sponsor:
National Center for Research Resources NCRR
Organization:
National Center for Research Resources NCRR
Study Overview
Official Title:
None
Status:
UNKNOWN
Status Verified Date:
2000-04
Last Known Status:
ACTIVE_NOT_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The two major types of diabetes are type 1 and type 2 diabetes Although most patients with type 2 diabetes are older than age 40 type 2 diabetes has been reported with increasing frequency among patients under the age of 20 This form of diabetes has been called type 2 diabetes of youth abbreviated type 2Y Little is known about the etiology of type 2Y however clinicians believe that it occurs most commonly in obese children of particular ethnic groups A positive family history appears to be one major risk factor for developing type 2Y diabetes The individual contribution of ethnicity obesity and genetics to type 2Y have yet to be elucidated There is no consensus regarding treatment with type 2Y diabetes Observation of our Hispanic patients in the Houston area reveals a large number with type 2Y The major purpose of this study is to examine the genetic and environmental risk factors such as family history ethnicity and obesity in Hispanic children with type 2Y diabetes SPECIFIC AIMS 1 To examine the genetic and environmental risk factors and clinical signs associated with type 1 diabetes and type 2 diabetes of youth 2 To compare the efficacy of the treatment modalities insulin and oral agents in type 2Y patients METHODS We will undertake a retrospective case study to include a review of hypothesized risk factors in all the medical records of pediatric diabetes patients seen at University of Texas We anticipate that approximately 200 patients with type 1 diabetes and 30 patients with type 2Y diabetes will be identified A Sustacal challenge test will be done in patients with a suspected diagnosis of type 2Y in order to confirm the clinical diagnosis Parents will be contacted by phone for a detailed pedigree intake Type 1 and type 2Y patients will be compared for each of the studied features A retrospective review of diabetes type 2 therapies used in type 2Y patients will be undertaken through further examination of the medical records in order to compare insulin treatment to oral agents We will also test a subset of the patients for the gene identified in adult Hispanics with type 2 diabetes
Detailed Description:
None
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| M01RR002558 | NIH | None | httpsreporternihgovquickSearchM01RR002558 |