Ignite Creation Date:
2024-05-06 @ 5:42 PM
Last Modification Date:
2024-10-26 @ 2:34 PM
Study NCT ID:
NCT05407077
Status:
COMPLETED
Last Update Posted:
2023-09-01
First Post:
2022-06-02
Brief Title:
Is Lower Limb Neuromotor Control Diverse in Females With PF OA Contrasted With Asymptomatic Controls
Sponsor:
Cairo University
Organization:
Cairo University
Study Overview
Official Title:
Is Lower Limb Neuromotor Control Diverse in Females With PF OA Contrasted With Asymptomatic Controls When Performing Stair Descent Task
Status:
COMPLETED
Status Verified Date:
2023-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Objective to investigate whether females with PF OA descend stairs with different muscular recruitment strategies contrasted with similar aged healthy females
Methods An observational comparative study will be conducted with thirty females with PF OA and 10 healthy ones The onset times and electromyography EMG duration of multifidus transversus abdominus TrA gluteus medius GM and vasti muscles will be measured by quantitative EMG during stair descent task hypothesis Investigators hypothesize that there wont be a significant difference between females with PF OA and their matched healthy group regarding the onset times and duration of vastus medialis obliqus VMO vastus lateralis VL gluteus medius GM multifidus and transversus abdominus TrA during stair descent task
Methods An observational comparative study will be conducted with thirty females with PF OA and 10 healthy ones The onset times and electromyography EMG duration of multifidus transversus abdominus TrA gluteus medius GM and vasti muscles will be measured by quantitative EMG during stair descent task hypothesis Investigators hypothesize that there wont be a significant difference between females with PF OA and their matched healthy group regarding the onset times and duration of vastus medialis obliqus VMO vastus lateralis VL gluteus medius GM multifidus and transversus abdominus TrA during stair descent task
Detailed Description:
Investigators will collect the EMG activity of VMO VL GM multifidus and TrA using bipolar Ag-AgCl disposable surface electrodes Better signal solution medical supply Co limited Zhongshan China and eight channels highresolution wireless bio amplifier WBA system Biomation Almonte Canada Electromyographic data will be sampled at 1000 Hz and bandpass filtered at 50-200 Hz For each muscle three electrodes will be used two electrodes will be placed 30 mm apart in the direction of the muscle fibers and a ground electrode will be placed over the closest bony prominence Before placement of the electrodes the subjects skin will be cleaned with alcohol to reduce impedance and excess hair will be removed to eliminate shifting of the electrodes if needed The stair-stepping task consists of descending 2 steps Patients should start descending the steps immediately in response to a command at their normal speed with their affected limb Healthy subjects should start descending stairs with their dominant limb Before data acquisition participants should perform one practice trial of stair descent to get familiarized with the task Then the participants should perform three test trials with thirty seconds of rest after each trial to prevent fatigue The raw data will be stored on a personal computer for analysis with a custom program in Matlab Math Works Natick Massachusetts USA Investigators should use a mean of data in three trials for analysis
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None