Ignite Creation Date:
2024-05-05 @ 5:36 PM
Last Modification Date:
2024-10-26 @ 9:34 AM
Study NCT ID:
NCT00496249
Status:
COMPLETED
Last Update Posted:
2015-12-22
First Post:
2007-07-03
Brief Title:
The Effect of Radiation on Semen Quality and Fertility in Men With Prostate Cancer
Sponsor:
University Health Network Toronto
Organization:
University Health Network Toronto
Study Overview
Official Title:
The Effect of Radiation on Semen Quality and Fertility in Men Treated With External Beam Radiation or Brachytherapy for Early Stage Prostate Cancer
Status:
COMPLETED
Status Verified Date:
2015-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Many younger men are diagnosed with prostate cancer These patients are often choosing radiation therapy as their primary treatment The effect of this therapy on fertility will have a direct impact on their decision about therapeutic options and fertility preservation The researchers hypothesize that when patients are treated with radiation for localized prostate cancer infertility can occur due to direct damage to seminiferous tubules affecting sperm quality
Detailed Description:
Prostate cancer is the most common malignant disease among men Many young men are diagnosed with localized prostate cancer Some of these men are choosing to manage their prostate cancer with radiation therapy The radiation therapy delivers minimal dose exposure to adjacent organs We hypothesize that when patients are treated with radiation therapy for localized prostate cancer decreased fertility can occur due to damage of seminiferous tubules which may affect sperm quality This study will assess the impact of radiation therapy on semen and seminal fluid
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None