Ignite Creation Date:
2024-05-05 @ 5:36 PM
Last Modification Date:
2024-10-26 @ 9:34 AM
Study NCT ID:
NCT00491387
Status:
TERMINATED
Last Update Posted:
2018-02-07
First Post:
2007-06-21
Brief Title:
Sympathetic Nervous System Modulation in Hypertension
Sponsor:
University of Cincinnati
Organization:
University of Cincinnati
Study Overview
Official Title:
Sympathetic Nervous System Modulation in Hypertension by Beta-adrenergic Blockade
Status:
TERMINATED
Status Verified Date:
2018-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Adverse events reported with beta-blockers as primary therapy
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This is a study of patients with high blood pressure who are already treated with an angiotensin converting enzyme inhibitor or receptor blocker and have achieved good or fair blood pressure control The hypothesis is that addition of the beta-adrenergic receptor blocker sustained-release metoprolol will provide additional blockade of the sympathetic nervous system thereby further improving left ventricular filling and blood pressure control
Detailed Description:
Patients were to receive sympathetic cardiac innervation testing with I-123 MIBG at baseline and again after receiving a titrate dose of beta-blocker Data were to be assesses by repeated measures testing
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None