Ignite Creation Date:
2024-05-06 @ 5:32 PM
Last Modification Date:
2024-10-26 @ 2:30 PM
Study NCT ID:
NCT05341037
Status:
COMPLETED
Last Update Posted:
2022-08-08
First Post:
2022-04-17
Brief Title:
Red Cell Distribution With to Lymphocyte Ratio in Cardiac Surgery
Sponsor:
Ankara City Hospital Bilkent
Organization:
Ankara City Hospital Bilkent
Study Overview
Official Title:
A Novel Biomarker for the Prediction of Early Comorbidity in Cardiac Surgery Red Cell Distribution With to Lymphocyte Ratio
Status:
COMPLETED
Status Verified Date:
2022-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
It is aimed to investigate whether red cell distribution with RDW to lymphocyte ratio RLR can predict early comorbidity among cardiac surgery patients
Detailed Description:
There are important developments in the field of cardiac surgery due to advances in medical treatments surgical techniques intraoperative anesthesia management and postoperative intensive care On the other hand the proportion of high-risk patients has increased due to the increasing number of elderly patients with comorbidities presenting for cardiac surgery It is important to analyze outcomes such as postoperative morbidity and mortality due to concerns about the quality of life of patients after cardiac operations the recommendations of current ERAS protocols and the shortening of intensive care unit length of stay Complications such as cardiac pulmonary renal and neurological disorders infections such as pneumonia or sepsis and prolonged stay in the intensive care unit and hospital are indicators of not only the quality of care but also the quality of life after cardiac surgery Therefore it is important to determine the perioperative risk factors that cause postoperative morbidity Various outcome prediction models are used for cardiac surgery such as the Cardiac Anesthesia Risk Assessment score Tuman score Tu score and the European System for Cardiac Operative Risk Assessment score which uses preoperative factors to predict the postoperative outcomes It is known that intraoperative factors such as CPB duration aortic cross-clamp time surgical technique and serum lactate levels are associated with postoperative morbidity Recent studies suggest that inflammatory and immune imbalance may play an important role in postoperative complications Studies point to new parameters derived from preoperative complete blood count as potential biomarkers of inflammation and oxidative stress Many markers such as NeutrophilLymphocyte ratio Mean platelet volume MPV or RDW alone have been studied in cardiac surgery The ratio of red cell distribution width RDW to lymphocyte L has been popular in recent years as an indicator of poor prognosis especially in oncological patients However this marker has not yet been evaluated in terms of morbidity or mortality in cardiac surgery patients
The main purpose of this study To investigate the RDWL ratio as an early morbidity marker in cardiac surgery patients
The main purpose of this study To investigate the RDWL ratio as an early morbidity marker in cardiac surgery patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None