Ignite Creation Date:
2024-05-06 @ 5:30 PM
Last Modification Date:
2024-10-26 @ 2:30 PM
Study NCT ID:
NCT05330806
Status:
RECRUITING
Last Update Posted:
2023-03-10
First Post:
2022-03-24
Brief Title:
Collagenase Chemonucleolysis vs Percutaneous Endoscopic Lumbar Discectomy PELD for Lumbar Disc Herniation
Sponsor:
Shenzhen Peoples Hospital
Organization:
Shenzhen Peoples Hospital
Study Overview
Official Title:
Collagenase Chemonucleolysis vs Percutaneous Endoscopic Lumbar Discectomy PELD for Lumbar Disc Herniation a Randomized Controlled Trial
Status:
RECRUITING
Status Verified Date:
2023-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Lumbar disc herniation compressed the nerve cause pain numbness weak legs called sciatica which seriously decrease the quality of life and work efficiency Both collagenase chemonucleolysisCCNL and percutaneous endoscopic lumbar discectomy PELD was effective to treat lumbar disc herniationLDH requires surgery whether functional clinical outcomes of CCNL vs PELD effect on LDH was superior and no study provided convincing evidence
Detailed Description:
Lumbar disc herniation LDH is a common disease with an incidence of 1-3 usually manifested as low back pain radiating to the lower extremities which seriously affects patients quality of life Collagen hydrolysis was effective in treating LDH it makes the protrusion smaller or disappeared relieving or resolving the compression of nerve root by the protrusionPercutaneous endoscopic lumbar discectomy PELD is a less invasive techniques to treat LDH However the outcomes of collagen hydrolysis vs PELD effect was still unknown
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None