Ignite Creation Date:
2024-05-06 @ 5:30 PM
Last Modification Date:
2024-10-26 @ 2:29 PM
Study NCT ID:
NCT05324085
Status:
RECRUITING
Last Update Posted:
2024-06-04
First Post:
2022-04-04
Brief Title:
Aerobic Exercise for Cognitive Functioning in Patients With Substance Use Disorder
Sponsor:
St Olavs Hospital
Organization:
St Olavs Hospital
Study Overview
Official Title:
Aerobic Exercise for Cognitive Functioning in Patients With Substance Use Disorder a Randomized Controlled Trial
Status:
RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
SO_CogEx
Brief Summary:
Impaired cognitive function is common among patients with substance use disorder SUD This is particularly related to executive functions EF which includes abilities like decision-making consequence analysis and impulseself-control EF is recognized as an important determinant of treatment outcome as it is associated with dropout rate attendance to therapy sessions and absence of relapse following treatment termination Exercise seem to improve cognitiveexecutive functions particularly in individuals with cognitive impairments Aerobic exercise also affects signaling substances and growth factors known to inhibit neural degeneration and improves cerebral insulin sensitivity and blood flow contributing to improved brain function There is a lack of knowledge regarding how to improve EF in SUD patients and whether such improvements can benefit other parts of the treatment such as psychotherapy Aerobic exercise is a well-recognized and cost-effective intervention for cardiovascular and metabolic health with promising effects on cognitiveexecutive functions A randomized controlled trial will be carried out to investigate the effects of aerobic exercise on EF molecular markers of neuroplasticity and brain function and treatment outcome in SUD patients The investigators expect to achieve new knowledge regarding cognitive impairment among SUD patients and to what extent aerobic exercise can improve cognitive abilities and treatment outcome
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 3253020430 | OTHER_GRANT | Central Norway Regional Health Authority | None |