Ignite Creation Date:
2025-12-24 @ 6:40 PM
Ignite Modification Date:
2025-12-28 @ 10:11 PM
Study NCT ID:
NCT06557057
Status:
RECRUITING
Last Update Posted:
2025-09-22
First Post:
2024-08-13
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Impact of Aromatase Inhibitor Therapy on Glucose Homeostasis and Diabetes Risk
Sponsor:
Mayo Clinic
Organization:
Study Overview
Official Title:
Impact of Aromatase Inhibitor Therapy on Glucose Homeostasis and Diabetes Risk
Status:
RECRUITING
Status Verified Date:
2025-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study assesses the effect of hormone directed treatment for breast cancer on glucose metabolism.
Detailed Description:
PRIMARY OBJECTIVE:
I. Assess the impact of endocrine adjuvant therapy with aromatase inhibitors in women with hormone receptor positive breast cancer or ductal carcinoma in situ (DCIS) on various indices of glucose homeostasis, utilizing oral minimal model assessment, in comparison to healthy post menopausal women and another cohort of women on tamoxifen.
OUTLINE: This is an observational study.
Patients undergo blood sample collection, glucose testing, dual-energy x-ray absorptiometry (DEXA)scan to measure body composition, complete a questionnaire and have their medical records reviewed on study.
I. Assess the impact of endocrine adjuvant therapy with aromatase inhibitors in women with hormone receptor positive breast cancer or ductal carcinoma in situ (DCIS) on various indices of glucose homeostasis, utilizing oral minimal model assessment, in comparison to healthy post menopausal women and another cohort of women on tamoxifen.
OUTLINE: This is an observational study.
Patients undergo blood sample collection, glucose testing, dual-energy x-ray absorptiometry (DEXA)scan to measure body composition, complete a questionnaire and have their medical records reviewed on study.
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: